Structural relationship between the putative hair cell mechanotransduction channel TMC1 and TMEM16 proteins
نویسندگان
چکیده
منابع مشابه
TMC1 and TMC2 Are Components of the Mechanotransduction Channel in Hair Cells of the Mammalian Inner Ear
Sensory transduction in auditory and vestibular hair cells requires expression of transmembrane channel-like (Tmc) 1 and 2 genes, but the function of these genes is unknown. To investigate the hypothesis that TMC1 and TMC2 proteins are components of the mechanosensitive ion channels that convert mechanical information into electrical signals, we recorded whole-cell and single-channel currents f...
متن کاملthe relationship between critical thinking and reading strategies
during the process of reading, sometimes learners use ineffective and inefficient strategies and some factors may influence their use of strategies. perhaps critical thinking is one of these factors. this study aims to identify those categories of reading strategies that are mostly used by iranian efl learners and to see if there is any significant relationship between the critical thinking abi...
Mechanotransduction: The Elusive Hair Cell Transduction Channel Revealed?
A family of transmembrane proteins has been shown to modulate both the calcium permeability and single-channel conductance of the vertebrate hair-cell mechanosensor, implicating them directly in inner ear mechanosensation.
متن کاملthe relationship between collocational competence and listening comprehension
پس از پیدایش روش تدریس tpr توسط جیمز اشر که توجه و تآکید بسیاری بر مهارت شنیداری داشت زبانشناسان همواره در صدد یافتن راههایی برای بهبود این مهارت در زبان آموزان می باشند. از طرفی جی-آر-فرث که از پیشگامان زبانشناسی می باشد بر تآثیر لغات و بویژه گروه کلمات که اغلب در گفتار با هم می آیند (هم آیی کلمات)تأکید بسیار کرده است. به این دلیل و به منظوربررسی رابطه بین این دو عامل یعنی درک شنیداری و دانش...
15 صفحه اولHair-Cell Mechanotransduction Persists in TRP Channel Knockout Mice
Members of the TRP superfamily of ion channels mediate mechanosensation in some organisms, and have been suggested as candidates for the mechanotransduction channel in vertebrate hair cells. Some TRP channels can be ruled out based on lack of an inner ear phenotype in knockout animals or pore properties not similar to the hair-cell channel. Such studies have excluded Trpv4, Trpa1, Trpml3, Trpm1...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: eLife
سال: 2018
ISSN: 2050-084X
DOI: 10.7554/elife.38433